Lady Cecilia with an Ermine

This is 'Lady Cecilia with an Emine' which is an oil painting by Leonardo da Vinci from 1489-1490. The subject of the portrait is Cecilia Gallerani, painted at a time when she was the mistress of Ludovico Sforza, Duke of Milan, and Leonardo was in the service of the duke. The painting is one of only four portraits of women painted by Leonardo, the others being the Mona Lisa, the portrait of Ginevra de' Benci, and La belle ferronnière. It is currently displayed at Wawel Royal Castle whilst renovations are carried out at the painting's home, Czartoryski Museum, Kraków, Poland.The painting travelled extensively during the 19th century; Princess Czartoryska rescued it in advance of the invading Russian army in 1830, hid it, then sent it to Dresden and on to the Czartoryski place of exile in Paris, the Hôtel Lambert, returning it to Kraków in 1882. In 1939, almost immediately after the German occupation of Poland, it was seized by the Nazis and sent to the Kaiser Friedrich Museum in Berlin. In 1940, Hans Frank, the Governor General of Poland, requested it be returned to Kraków, where it hung in his suite of offices. At the end of the Second World War it was discovered by Allied troops in Frank's country home in Bavaria.
http://www.wawel.krakow.pl/en/index.php?op=125

The history of the portrait is what Will based his game on hence the Nazi's, Lady Cecilia and the Ermine being the Characters. 

http://www.allposters.com/-sp/Cecilia-Gallerani-Mistress-of-Ludovico-Sforza-Portrait-Known-as-Lady-with-the-Ermine-c-1490-Posters_i6235715_.htm